http://www.snes9x.com/phpbb2/viewtopic.php?p=12712
http://bugs.gentoo.org/104049

--- snes9x/configure.in
+++ snes9x/configure.in
@@ -585,6 +585,19 @@
   SYSDEFINES="$SYSDEFINES"' -DHAVE_SYS_IOCTL_H'
 ])
 
+AC_CHECK_HEADER(endian.h, [
+  SYSDEFINES="$SYSDEFINES"' -DHAVE_ENDIAN_H'
+])
+AC_CHECK_HEADER(sys/endian.h, [
+  SYSDEFINES="$SYSDEFINES"' -DHAVE_SYS_ENDIAN_H'
+])
+AC_CHECK_HEADER(machine/endian.h, [
+  SYSDEFINES="$SYSDEFINES"' -DHAVE_MACHINE_ENDIAN_H'
+])
+AC_CHECK_HEADER(sys/isa_defs.h, [
+  SYSDEFINES="$SYSDEFINES"' -DHAVE_SYS_ISA_DEFS_H'
+])
+
 AC_CHECK_HEADERS(unistd.h sys/socket.h winsock.h winsock2.h WS2tcpip.h)
 
 
--- snes9x/port.h.orig	2005-08-28 16:57:03.000000000 -0400
+++ snes9x/port.h	2005-08-28 17:11:59.000000000 -0400
@@ -110,6 +110,19 @@
 
 #include <sys/types.h>
 
+#if defined(HAVE_ENDIAN_H)
+# include <endian.h>
+#endif
+#if defined(HAVE_SYS_ENDIAN_H)
+# include <sys/endian.h>
+#endif
+#if defined(HAVE_MACHINE_ENDIAN_H)
+# include <machine/endian.h>
+#endif
+#if defined(HAVE_SYS_ISA_DEFS_H)
+# include <sys/isa_defs.h>
+#endif
+
 /* #define PIXEL_FORMAT RGB565 */
 #define GFX_MULTI_FORMAT
 
@@ -265,12 +278,27 @@
 #define SIG_PF void(*)(int)
 #endif
 
-#if defined(__i386__) || defined(__i486__) || defined(__i586__) || \
-    defined(__WIN32__) || defined(__alpha__)
-#define LSB_FIRST
-#define FAST_LSB_WORD_ACCESS
-#else
-#define MSB_FIRST
+#if defined(BYTE_ORDER)
+# if BYTE_ORDER == LITTLE_ENDIAN
+#  define LSB_FIRST
+# else
+#  define MSB_FIRST
+# endif
+#elif defined(WORDS_LITTLENDIAN)
+# define LSB_FIRST
+#elif defined(WORDS_BIGENDIAN)
+# define MSB_FIRST
+#else
+# if defined(__i386__) || defined(__i486__) || defined(__i586__) || \
+    defined(__WIN32__) || defined(__alpha__) || defined(__x86_64__)
+#  define LSB_FIRST
+# else
+#  define MSB_FIRST
+# endif
+#endif
+
+#if defined(LSB_FIRST)
+# define FAST_LSB_WORD_ACCESS
 #endif
 
 #ifdef __sun